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Displaying 1 - 10 of 223 Projects
Project # Contact PI Funding Organization Fiscal Year
Treating with Gamma-Secretase Modulators to Prevent Neurodegeneration in Mouse Models of Down Syndrome and Alzheimer Disease
5R01AG055523-04 MOBLEY, WILLIAM C NIA 2021
Identify common mechanisms of neurodegeneration between Alzheimer's disease and Down syndrome
5R01AG059627-04 VELAZQUEZ, RAMON NIA 2021
Antisense Oligonucleotides targeting APP to prevent neurodegeneration in models of Down Syndrome and Alzheimer's disease
5R01AG061151-03 MOBLEY, WILLIAM C NIA 2021
Studies of dementia pathogenesis in genetically faithful rat models of Familal Alzheimer disease
5R01AG063407-03 D'ADAMIO, LUCIANO NIA 2021
A Novel Approach to Molecular Cell Pathologies of Human Down Syndrome and DS-AD
5R01HD091357-05 LAWRENCE, JEANNE BENTLEY NICHD 2021
Translational Epigenetics with XIST: Silencing Trisomy in Human Organoid and Mouse Models of Down Syndrome
5R01HD094788-04 LAWRENCE, JEANNE BENTLEY NICHD 2021
Altered Hippocampal Neurogenesis and Cognition via Maneb-mediated Changes in the Thiol Redox Proteome.
5R01ES027593-05 ROEDE, JAMES R NIEHS 2021
Function and dysfunction of REST in neurodegeneration
5K22NS107802-03 FERNANDEZ, MARTY NINDS 2021
Treating with Gamma-Secretase Modulators to Prevent Neurodegeneration in Mouse Models of Down Syndrome and Alzheimer Disease
5R01AG055523-03 MOBLEY, WILLIAM C NIA 2020
Identify common mechanisms of neurodegeneration between Alzheimer's disease and Down syndrome
5R01AG059627-03 VELAZQUEZ, RAMON NIA 2020