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Displaying 1 - 10 of 18 Projects
Project # Contact PI Funding Organization Fiscal Year
Antisense Oligonucleotides targeting APP to prevent neurodegeneration in models of Down Syndrome and Alzheimer's disease
1R01AG061151-01 MOBLEY, WILLIAM C NIA 2019
Studies of dementia pathogenesis in genetically faithful rat models of Familal Alzheimer disease
1R01AG063407-01 D'ADAMIO, LUCIANO NIA 2019
Introducing Cellular Aging in Human iPS Cells to Investigate Alzheimer Pathogenesis
3RF1AG056302-01S1 ZHANG, HONG NIA 2019
Treating with Gamma-Secretase Modulators to Prevent Neurodegeneration in Mouse Models of Down Syndrome and Alzheimer Disease
5R01AG055523-02 MOBLEY, WILLIAM C NIA 2019
Identify common mechanisms of neurodegeneration between Alzheimer's disease and Down syndrome
5R01AG059627-02 VELAZQUEZ, RAMON NIA 2019
Neurodegeneration in Aging Down Syndrome (NiAD): A Longitudinal Study of Cognition and Biomarkers of Alzheimer's Disease
5U01AG051406-05 HANDEN, BENJAMIN L NIA 2019
Biomarkers of Alzheimer's Disease in Adults with Down Syndrome
5U01AG051412-05 SCHUPF, NICOLE NIA 2019
Modeling Down Syndrome Neural Phenotypes with Chromosomal Silencing
5F30HD086975-03 CZERMINSKI, JAN NICHD 2019
Aging and Dementia in Down Syndrome: Connectivity; Inflammation; and Cerebrovascular Contributions
5R01HD064993-10 SCHMITT, FREDERICK NICHD 2019
A Novel Approach to Molecular Cell Pathologies of Human Down Syndrome and DS-AD
5R01HD091357-03 LAWRENCE, JEANNE BENTLEY NICHD 2019