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Displaying 1 - 10 of 21 Projects
Project # Contact PI Funding Organization Fiscal Year
Human CNS tau kinetics in tauopathies
AFTD-Bateman-2017 Bateman, Randall The Association for Frontotemporal Degeneration 2017
Identification and validation of novel MAPT splicing factors and RNA-binding proteins
AFTD-Bowles-2017 Bowles, Kathryn The Association for Frontotemporal Degeneration 2017
Detection of misfolded TDP-43 protein in CSF and plasma of GRN and C9orf72 mutation carriers
AFTD-Caroppo-2017 Caroppo, Paola The Association for Frontotemporal Degeneration 2017
Nucleocytoplasmic transport defects perturb granular flux In FTD
AFTD-Clarke-2017 Clarke, Joseph-Patrick The Association for Frontotemporal Degeneration 2017
Novel human FTLD neuron and microglia cell models for drug discovery
AFTD-Finkbeiner-2017 Finkbeiner, Steven The Association for Frontotemporal Degeneration 2017
sTREM2, PGRN, and GRN as CSF markers for microglial activity, disease progression, and therapeutic target engagement
AFTD-Haass-2017 Haass, Christian The Association for Frontotemporal Degeneration 2017
Rescue of lysosomal dysfunction, neuroinflammation, and neurodegeneration by lysosomal GRN-2 in a mouse model of PGRN deficiency and frontotemporal dementia
AFTD-Kukar-2017 Kukar, Thomas The Association for Frontotemporal Degeneration 2017
Tau and adult neurogenesis. Therapeutic potential for frontotemporal degeneration
AFTD-Llorens-Martí-2017 Llorens-Martín, María The Association for Frontotemporal Degeneration 2017
Assessing polyGP proteins as clinical and pharmacodynamic biomarkers of C9ORF72-associated FTD
AFTD-Petrucelli-2017 PETRUCELLI, LEONARD The Association for Frontotemporal Degeneration 2017
Identification of novel biofluid markers of tau and TDP-43 pathology
AFTD-Rohrer-2017 Rohrer, Jonathan The Association for Frontotemporal Degeneration 2017