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Displaying 1 - 10 of 11 Projects
Project # Contact PI Funding Organization Fiscal Year
Development of a PIKFYVE antisense oligonucleotide (ASO) treatment for FTD
ADDF-2 Chang, Wen-Hsuan Alzheimer's Drug Discovery Foundation 2020
Development of Small Molecules Modulators of Mitochondrial Function
ADDF-29 TRUSHINA, EUGENIA Alzheimer's Drug Discovery Foundation 2020
Restoration of healthy Wnt signalling in the neurovascular unit through inhibition of Notum carboxylesterase activity: a Lead to Preclinical Candidate Program for Alzheimer's disease
ADDF-3 Fish, Paul Alzheimer's Drug Discovery Foundation 2020
Preclinical efficacy study for antibody therapy in C9orf72 FTD/ALS mice
ADDF-30 Edbauer, Dieter Alzheimer's Drug Discovery Foundation 2020
Lead Optimization of Novel Site-Selective Blockers of Mitochondrial Complex III ROS as FTD Therapeutics
ADDF-4 Orr, Anna Alzheimer's Drug Discovery Foundation 2020
6th Annual Goodes Prize for Excellence in Alzheimer's Drug Discovery: Development of mGlu5 negative or silent allosteric modulators for the treatment of Alzheimer's disease
ADDF-9 Rook, Jerri Alzheimer's Drug Discovery Foundation 2020
Novel human FTLD neuron and microglia cell models for drug discovery
GA-2013790 Finkbeiner, Steven Alzheimer's Drug Discovery Foundation 2017
Rescue of lysosomal dysfunction, neuroinflammation, and neurodegeneration by lysosomal GRN-2 in a mouse model of PGRN deficiency and Frontotemporal Dementia
GA-2013863 Kukar, Thomas Alzheimer's Drug Discovery Foundation 2017
Activation of microglial cells to promote clearance of amyloid-beta
GC-2013257 Parker, Michael Alzheimer's Drug Discovery Foundation 2017
Optimization of selective DYRK1A inhibitors as a treatment for AD
GC-2013749 HULME, CHRISTOPHER Alzheimer's Drug Discovery Foundation 2017