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Displaying 1 - 7 of 7 Projects
Project # Contact PI Funding Organization Fiscal Year
Rescue of lysosomal dysfunction, neuroinflammation, and neurodegeneration by lysosomal GRN-2 in a mouse model of PGRN deficiency and Frontotemporal Dementia
GC-2013863 Kukar, Thomas Alzheimer's Drug Discovery Foundation 2017
Mitochondrial TDP-43 as a Novel Therapeutic Target for FTD
GC-2013162 WANG, XINGLONG Alzheimer's Drug Discovery Foundation 2016
A novel neuroprotective compound targeting endogenous function of C9ORF72 in vivo
GC-2013194 Ichida, Justin Alzheimer's Drug Discovery Foundation 2016
FTD Trafficking Assays and Compound Screening: Inhibiting Sortilin-dependent progranulin endocytosis.
20141106-Sneddon-2014 Sneddon, Scott Alzheimer's Drug Discovery Foundation 2014
The effect of novel heat shock protein 90 (Hsp90) inhibitors on total and phosphorylated tau levels in cerebrospinal fluid and memory deficits in the hTAU441 (tauopathy) mouse transgenic model of Alzheimer's disease
20131003-PERRELLA-2013 PERRELLA, YUKARI Alzheimer's Drug Discovery Foundation 2013
Biomarker Optimization for Progranulin Trials
20111104 AFTD-Boxer-2011 BOXER, ADAM L Alzheimer's Drug Discovery Foundation 2011
Hsp90 inhibitors in tauopathies: in vivo pre-clinical development
281207 AFTD-CHIOSIS-2008 CHIOSIS, GABRIELA Alzheimer's Drug Discovery Foundation 2008