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Displaying 1 - 10 of 15 Projects
Project # Contact PI Funding Organization Fiscal Year
A single-center, randomized, placebo-controlled single & multiple ascending dose study in healthy subjects to study the safety, tolerability, food effect, pharmacokinetics and target engagement of the second-generation O-GlcNAcase inhibitor ASN121151
ADDF-1 Beher, Dirk Alzheimer's Drug Discovery Foundation 2020
AFTD Patient-Focused Drug Development Meeting with the FDA
ADDF-10 Dickinson, Susan Alzheimer's Drug Discovery Foundation 2020
A Placebo Controlled, Randomized Double-blind Parallel Group 12-month Trial of Fasudil for the Treatment of Mild Cognitive Impairment Due to Alzheimer's disease, nested within a Multi-Arm Phase 2 Clinical Trial Platform
ADDF-13 Ballard, Clive Alzheimer's Drug Discovery Foundation 2020
MET-FINGER-APOE: A randomized controlled trial of multimodal lifestyle intervention and metformin to prevent cognitive impairment and disability in a cognitively healthy APOE4 enriched at-risk population
ADDF-14 Kivipelto, Miia Alzheimer's Drug Discovery Foundation 2020
Development of a PIKFYVE antisense oligonucleotide (ASO) treatment for FTD
ADDF-2 Chang, Wen-Hsuan Alzheimer's Drug Discovery Foundation 2020
Phase II Clinical Trial to Evaluate the Safety and Feasibility of Senolytic Therapy in Alzheimer's Disease
ADDF-25 Orr, Miranda Alzheimer's Drug Discovery Foundation 2020
Phase I Clinical Trial for the AAV mediated treatment of APOE4 homozygous Alzheimer's Disease
ADDF-26 Crystal, Ronald Alzheimer's Drug Discovery Foundation 2020
Development of Small Molecules Modulators of Mitochondrial Function
ADDF-29 TRUSHINA, EUGENIA Alzheimer's Drug Discovery Foundation 2020
Restoration of healthy Wnt signalling in the neurovascular unit through inhibition of Notum carboxylesterase activity: a Lead to Preclinical Candidate Program for Alzheimer's disease
ADDF-3 Fish, Paul Alzheimer's Drug Discovery Foundation 2020
Preclinical efficacy study for antibody therapy in C9orf72 FTD/ALS mice
ADDF-30 Edbauer, Dieter Alzheimer's Drug Discovery Foundation 2020