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Displaying 1 - 10 of 14 Projects
Project # Contact PI Funding Organization Fiscal Year
Rescue of lysosomal dysfunction, neuroinflammation, and neurodegeneration by lysosomal GRN-2 in a mouse model of PGRN deficiency and frontotemporal dementia
AFTD-Kukar-2017 Kukar, Thomas The Association for Frontotemporal Degeneration 2017
A novel neuroprotective compound targeting endogenous function of C9ORF72 in vivo
AFTD-Ichida-2016 Ichida, Justin The Association for Frontotemporal Degeneration 2016
Mitochondrial TDP-43 as a Novel Therapeutic Target for FTD
AFTD-Wang-2016 WANG, XINGLONG The Association for Frontotemporal Degeneration 2016
Low-dose lithium for the treatment of behavioral symptoms in FTD
AFTD-Huey-2015 Huey, Edward The Association for Frontotemporal Degeneration 2015
Lead optimization and pre-clinical testing of small molecules that modulate toxicity of c9FTD/ALS
AFTD-Disney-2014 Disney, Matthew The Association for Frontotemporal Degeneration 2014
Brain slice screen for microRNA targeted drug lead candidates for tau-associated FTD
AFTD-Lo-2013 Lo, Donald The Association for Frontotemporal Degeneration 2013
FTD C9ORF72 Based Biomarkers for Antisense-based Drug Discovery Validation
AFTD-Rothstein-2013 Rothstein, Jeffrey The Association for Frontotemporal Degeneration 2013
Restoring progranulin in frontotemporal disease
AFTD-Cairns-2012 Cairns, Nigel The Association for Frontotemporal Degeneration 2012
Development of Antisense therapy and Therapeutic biomarker for C9orf72 FTD/ALS mutation patients
AFTD-Rothstein-2012 Rothstein, Jeffrey The Association for Frontotemporal Degeneration 2012
Development of small molecule enhancers of autophagy for the clearance of protein aggregates and treatment of FTD
AFTD-Yu-2012 Yu, W. Haung The Association for Frontotemporal Degeneration 2012