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Displaying 1 - 10 of 44 Projects
Project # Contact PI Funding Organization Fiscal Year
A randomized, double blind, placebo-controlled study to evaluate the impact of Nilotinib treatment on safety, tolerability, pharmacokinetics and biomarkers in Dementia with Lewy Bodies (DLB)
5R01AG062463-03 MOUSSA, CHARBEL NIA 2021
Impact of Anticholinergic and Dopamine Receptor Blocking Drug Exposure on Parkinson Disease Trajectory and Outcomes
5R01NS099129-05 WILLIS, ALLISON NINDS 2021
Stabilizing native α-synuclein homeostasis to prevent insoluble α-synuclein aggregates
5R01NS099328-05 DETTMER, ULF NINDS 2021
Increasing butyrate levels by microbiome manipulation or drug administration to delay Parkinsons disease progression.
5F31AT010095-03 GARCIA, STEPHANIE MICHELLE NCCIH 2020
A randomized; double blind; placebo-controlled study to evaluate the impact of Nilotinib treatment on safety; tolerability; pharmacokinetics and biomarkers in Dementia with Lewy Bodies (DLB)
5R01AG062463-02 MOUSSA, CHARBEL NIA 2020
Structural and biological characterization of a novel pan-amyloid; protofibril capping protein for the rational design of therapeutics that target age related amyloidosis syndromes
5R21AG061605-02 SAKMAR, THOMAS P NIA 2020
Isolating small-molecule enhancers of the human alpha-synuclein disaggregase machinery
5R21AG061784-02 SHORTER, JAMES NIA 2020
Impact of Anticholinergic and Dopamine Receptor Blocking Drug Exposure on Parkinson Disease Trajectory and Outcomes
5R01NS099129-04 WILLIS, ALLISON NINDS 2020
Stabilizing native ?-synuclein homeostasis to prevent insoluble ?-synuclein aggregates
5R01NS099328-04 DETTMER, ULF NINDS 2020
Targeting Lewy Body Specific Pathology Using Biomarkers
5U01NS100600-05 MARDER, KAREN S NINDS 2020