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Displaying 1 - 10 of 11 Projects
Project # Contact PI Funding Organization Fiscal Year
Treating with Gamma-Secretase Modulators to Prevent Neurodegeneration in Mouse Models of Down Syndrome and Alzheimer Disease
5R01AG055523-03 MOBLEY, WILLIAM C NIA 2020
Identify common mechanisms of neurodegeneration between Alzheimer's disease and Down syndrome
5R01AG059627-03 VELAZQUEZ, RAMON NIA 2020
Antisense Oligonucleotides targeting APP to prevent neurodegeneration in models of Down Syndrome and Alzheimer's disease
5R01AG061151-02 MOBLEY, WILLIAM C NIA 2020
Studies of dementia pathogenesis in genetically faithful rat models of Familal Alzheimer disease
5R01AG063407-02 D'ADAMIO, LUCIANO NIA 2020
Modeling Down Syndrome Neural Phenotypes with Chromosomal Silencing
5F30HD086975-04 CZERMINSKI, JAN NICHD 2020
A Novel Approach to Molecular Cell Pathologies of Human Down Syndrome and DS-AD
5R01HD091357-04 LAWRENCE, JEANNE BENTLEY NICHD 2020
Translational Epigenetics with XIST: Silencing Trisomy in Human Organoid and Mouse Models of Down Syndrome
5R01HD094788-03 LAWRENCE, JEANNE BENTLEY NICHD 2020
Altered Hippocampal Neurogenesis and Cognition via Maneb-mediated Changes in the Thiol Redox Proteome.
5R01ES027593-04 ROEDE, JAMES R NIEHS 2020
Function and dysfunction of REST in neurodegeneration
5K22NS107802-02 FERNANDEZ, MARTY NINDS 2020
Targeting Lewy Body Specific Pathology Using Biomarkers
5U01NS100600-05 MARDER, KAREN S NINDS 2020