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Displaying 1 - 10 of 26 Links/Repositories
ID/Name Source Type
[AlzPED] A novel p38 alpha MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model.
17784957 Alzheimer's Disease Preclinical Efficacy Database (AlzPED) Repository
[AlzPED] AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy.
28416651 Alzheimer's Disease Preclinical Efficacy Database (AlzPED) Repository
[AlzPED] Affinity of Tau antibodies for solubilized pathological Tau species but not their immunogen or insoluble Tau aggregates predicts in vivo and ex vivo efficacy
27578006 Alzheimer's Disease Preclinical Efficacy Database (AlzPED) Repository
[AlzPED] An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice
16769887 Alzheimer's Disease Preclinical Efficacy Database (AlzPED) Repository
[AlzPED] Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model.
28379300 Alzheimer's Disease Preclinical Efficacy Database (AlzPED) Repository
[AlzPED] Early stage drug treatment that normalizes proinflammatory cytokine production attenuates synaptic dysfunction in a mouse model that exhibits age-dependent progression of Alzheimer's disease-related pathology
22836255 Alzheimer's Disease Preclinical Efficacy Database (AlzPED) Repository
[AlzPED] Epothilone D Improves Microtubule Density, Axonal Integrity and Cognition in a Transgenic Mouse Model of Tauopathy
20943926 Alzheimer's Disease Preclinical Efficacy Database (AlzPED) Repository
[AlzPED] First-in-man tau vaccine targeting structural determinants essential for pathological tau-tau interaction reduces tau oligomerisation and neurofibrillary degeneration in an Alzheimer's disease model.
25478017 Alzheimer's Disease Preclinical Efficacy Database (AlzPED) Repository
[AlzPED] Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model.
21147995 Alzheimer's Disease Preclinical Efficacy Database (AlzPED) Repository
[AlzPED] Increased O-GlcNAcylation reduces pathological tau without affecting its normal phosphorylation in a mouse model of tauopathy
24326295 Alzheimer's Disease Preclinical Efficacy Database (AlzPED) Repository