Project Number 5R01AG044420-05 Agency/Funding Organization NIA Funding Year 2017 View Full Project Details for Roles of SN27 in regulating glutamate receptors during neurodegeneration Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category A. Molecular Pathogenesis and Physiology of Alzheimer's Disease and Alzheimer's Disease-related Dementias (AD/ADRDs) 7. Circuits and Synapses c. Neurotransmitter Receptors Structure and Function Researcher and Organization Principal Investigator XU, HUAXI Principal Investigator First Name PAUL Principal Investigator Last Name GREENGARD Awardee Organization SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE Awardee State California Contact PI Country United States Project Detail Funding Opportunity Announcement PA-11-260: RESEARCH PROJECT GRANT (PARENT R01) FY Overall Cost $399,750 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official PETANCESKA, SUZANA Special Initiative Special Research Focus: Down Syndrome Related Resources Repository [AlzPED] Metformin promotes tau aggregation and exacerbates abnormal behavior in a mouse model of tauopathy