Project Number 1RF1AG048099-01 Agency/Funding Organization NIA Funding Year 2014 View Full Project Details for THE ROLE OF TREM2 IN HUMAN MICROGLIAL FUNCTION AND ALZHEIMER DISEASE PATHOGENESIS Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category A. Molecular Pathogenesis and Physiology of Alzheimer's Disease and Alzheimer's Disease-related Dementias (AD/ADRDs) 9. Immunity and Inflammation b. Microglia Category F. Research Resources 6. Disease Models e. iPS Cells Researcher and Organization Principal Investigator BLURTON-JONES, MATHEW MARK Principal Investigator First Name MATHEW MARK Principal Investigator Last Name BLURTON-JONES Awardee Organization UNIVERSITY OF CALIFORNIA IRVINE Awardee State California Contact PI Country United States Project Detail Funding Opportunity Announcement RFA-AG-14-012: Human Cell Reprogramming for Functional Genetics of Alzheimer's Disease (R01) FY Overall Cost $1,921,750 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official WISE, BRADLEY C Related Resources Repository [AlzPED] HuCNS-SC Human NSCs Fail to Differentiate, Form Ectopic Clusters, and Provide No Cognitive Benefits in a Transgenic Model of Alzheimer's Disease. [AlzPED] MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice