Project Number 5R01NS055161-05 Agency/Funding Organization NINDS Funding Year 2011 View Full Project Details for THE PRESENILINS AS G-PROTEIN COUPLED RECEPTORS Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category A. Molecular Pathogenesis and Physiology of Alzheimer's Disease and Alzheimer's Disease-related Dementias (AD/ADRDs) 3. Presenilin Biology b. Calcium Signaling Researcher and Organization Principal Investigator DEWJI, NAZNEEN N Principal Investigator First Name NAZNEEN Principal Investigator Last Name DEWJI Awardee Organization UNIVERSITY OF CALIFORNIA SAN DIEGO Awardee State California Contact PI Country United States Project Detail FY Overall Cost $331,209 Funding Organization Agency/Funding Organization NINDS Funding Organization Country United States Program Official CORRIVEAU, RODERICK A Related Resources Repository [AlzPED] Peptides of presenilin-1 bind the amyloid precursor protein ectodomain and offer a novel and specific therapeutic approach to reduce ß-amyloid in Alzheimer's disease Patent Methods and compositions for treating neurodegenerative disorders and alzheimer's disease and improving normal memory Methods and compositions for treating neurodegenerative disorders and Alzheimer's disease and improving normal memory Methods and compositions for treating neurodegenerative disorders and Alzheimer's disease and improving normal memory Methods and compositions for treating neurodegenerative disorders and Alzheimer'S disease and improving normal memory Methods for screening agents that modulate presenilin activity and A-.beta. production
