Project Number 5U01AG032225-03 Agency/Funding Organization NIA Funding Year 2009 View Full Project Details for P75 SMALL MOLECULE LIGANDS FOR ALZHEIMER'S THERAPY Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category C. Translational Research and Clinical Interventions 4. Non-clinical Drug Development (small molecules and biologics) a. Amyloid beta Researcher and Organization Principal Investigator LONGO, FRANK M Principal Investigator First Name FRANK Principal Investigator Last Name LONGO Awardee Organization STANFORD UNIVERSITY Awardee State California Contact PI Country United States Project Detail Funding Opportunity Announcement PAR-05-158: NINDS COOPERATIVE PROGRAM IN TRANSLATIONAL RESEARCH FY Overall Cost $861,856 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official BUCKHOLTZ, NEIL Related Resources Repository [AlzPED] A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression [AlzPED] Small Molecule p75NTR Ligands Reduce Pathological Phosphorylation and Misfolding of Tau, Inflammatory Changes, Cholinergic Degeneration, and Cognitive Deficits in AβPPL/S Transgenic Mice
