Project Number 5R01AG013741-11 Agency/Funding Organization NIA Funding Year 2010 View Full Project Details for NSAID INHIBITION OF ALZHEIMER PATHOLOGY: ROLE OF DHA Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category A. Molecular Pathogenesis and Physiology of Alzheimer's Disease and Alzheimer's Disease-related Dementias (AD/ADRDs) 4. ApoE and Lipid Neurobiology e. Lipid-Mediated Signaling Researcher and Organization Principal Investigator COLE, GREGORY M Principal Investigator First Name GREGORY M Principal Investigator Last Name COLE Awardee Organization UNIVERSITY OF CALIFORNIA LOS ANGELES Awardee State California Contact PI Country United States Project Detail FY Overall Cost $243,335 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official REFOLO, LORENZO Related Resources Repository [AlzPED] Ibuprofen Suppresses Interleukin-1β Induction of Pro-Amyloidogenic α1-Antichymotrypsin to Ameliorate β-Amyloid (Aβ) Pathology in Alzheimer’s Models [AlzPED] Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo [AlzPED] Docosahexaenoic Acid Protects from Dendritic Pathology in an Alzheimer’s Disease Mouse Model [AlzPED] The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse [AlzPED] Ibuprofen Suppresses Plaque Pathology and Inflammation in a Mouse Model for Alzheimer’s Disease
