Project Number 5R01AG047644-03 Agency/Funding Organization NIA Funding Year 2016 View Full Project Details for NOVEL STRATEGIES AND MECHANISMS TO TARGET APOE AND ALZHEIMER'S DISEASE Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category C. Translational Research and Clinical Interventions 3. Drug Discovery (small molecules and biologics) c. ApoE, Lipids and Lipoprotein Receptors Researcher and Organization Principal Investigator HOLTZMAN, DAVID M Principal Investigator First Name DAVID Principal Investigator Last Name HOLTZMAN Awardee Organization WASHINGTON UNIVERSITY IN SAINT LOUIS Awardee State Missouri Contact PI Country United States Project Detail Funding Opportunity Announcement PA-13-302: RESEARCH PROJECT GRANT (PARENT R01) FY Overall Cost $553,045 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official REFOLO, LORENZO Related Resources Repository [AlzPED] APOE Genotype Differentially Modulates Effects of Anti-Aβ, Passive Immunization in APP Transgenic Mice [AlzPED] Intracerebral adeno-associated virus gene delivery of apolipoprotein E2 markedly reduces brain amyloid pathology in Alzheimer's disease mouse models.