Project Number 5P01AG010485-18 Agency/Funding Organization NIA Funding Year 2009 View Full Project Details for NEUROPROTECTIVE ESTROGENS AND ALZHEIMER'S DISEASE Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category A. Molecular Pathogenesis and Physiology of Alzheimer's Disease and Alzheimer's Disease-related Dementias (AD/ADRDs) 12. Neuroendocrine Mechanisms a. Sex Hormones Researcher and Organization Principal Investigator SIMPKINS, JAMES W Principal Investigator First Name JAMES Principal Investigator Last Name SIMPKINS Awardee Organization University of North Texas Awardee State Texas Contact PI Country United States Project Detail FY Overall Cost $249,524 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official BUCKHOLTZ, NEIL Related Resources Repository [AlzPED] The alpha7 nicotinic receptor agonist 4OH-GTS-21 protects axotomized septohippocampal cholinergic neurons in wild type but not amyloid-overexpressing transgenic mice.