Project Number 1R01AG033568-01A2 Agency/Funding Organization NIA Funding Year 2010 View Full Project Details for THE NEUROBIOLOGY OF 5-LIPOXYGENASE Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category A. Molecular Pathogenesis and Physiology of Alzheimer's Disease and Alzheimer's Disease-related Dementias (AD/ADRDs) 4. ApoE and Lipid Neurobiology e. Lipid-Mediated Signaling Researcher and Organization Principal Investigator PRATICO, DOMENICO Principal Investigator First Name DOMENICO Principal Investigator Last Name PRATICO Awardee Organization TEMPLE UNIVERSITY Awardee State Pennsylvania Contact PI Country United States Project Detail Funding Opportunity Announcement PA-07-070: RESEARCH PROJECT GRANT (PARENT R01) FY Overall Cost $307,500 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official REFOLO, LORENZO Related Resources Repository [AlzPED] Pharmacologic Inhibition of 5-Lipoxygenase Improves Memory, Rescues Synaptic Dysfunction, and Ameliorates Tau Pathology in a Transgenic Model of Tauopathy [AlzPED] Zileuton restores memory impairments and reverses amyloid and tau pathology in aged Alzheimer's disease mice