Project Number 2R01AG018454-12A1 Agency/Funding Organization NIA Funding Year 2014 View Full Project Details for IMMUNE-MEDIATED MECHANISMS UNDERLYING CNS ABETA CLEARANCE Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category A. Molecular Pathogenesis and Physiology of Alzheimer's Disease and Alzheimer's Disease-related Dementias (AD/ADRDs) 1. Amyloid beta e. Amyloid beta Clearance Researcher and Organization Principal Investigator GOLDE, TODD E Principal Investigator First Name TODD Principal Investigator Last Name GOLDE Awardee Organization UNIVERSITY OF FLORIDA Awardee State Florida Contact PI Country United States Project Detail Funding Opportunity Announcement PA-11-260: RESEARCH PROJECT GRANT (PARENT R01) FY Overall Cost $435,633 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official PETANCESKA, SUZANA Related Resources Repository [AlzPED] Intracranial Adeno-Associated Virus-Mediated Delivery of Anti-Pan Amyloid β, Amyloid β40, and Amyloid β42 Single-Chain Variable Fragments Attenuates Plaque Pathology in Amyloid Precursor Protein Mice [AlzPED] Anti-Aβ42– and anti-Aβ40–specific mAbs attenuate amyloid deposition in an Alzheimer disease mouse model [AlzPED] Reduced effectiveness of Abeta1-42 immunization in APP transgenic mice with significant amyloid deposition