Project Number 5P01AG017586-12 Agency/Funding Organization NIA Funding Year 2012 View Full Project Details for GENETIC MODIFIERS OF TAUOPATHIES Research Categorization Primary Disease / Condition Frontotemporal Dementia CADRO Category A. Molecular Pathogenesis and Physiology of Alzheimer's Disease and Alzheimer's Disease-related Dementias (AD/ADRDs) 17. Genetics g. Disease Pathway Identification Researcher and Organization Principal Investigator SCHELLENBERG, GERARD DAVID Principal Investigator First Name GERARD DAVID Principal Investigator Last Name SCHELLENBERG Awardee Organization UNIVERSITY OF PENNSYLVANIA Awardee State Pennsylvania Contact PI Country United States Project Detail FY Overall Cost $289,455 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official MILLER, MARILYN Related Resources Repository [AlzPED] Passive immunization with phospho-tau antibodies reduces tau pathology and functional deficits in two distinct mouse tauopathy models. [AlzPED] Epothilone D Improves Microtubule Density, Axonal Integrity and Cognition in a Transgenic Mouse Model of Tauopathy [AlzPED] Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model