Project Number 5R01NS050895-14 Agency/Funding Organization NINDS Funding Year 2017 View Full Project Details for Combining AD Epitope Vaccine with Innate Immunity Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category C. Translational Research and Clinical Interventions 3. Drug Discovery (small molecules and biologics) a. Amyloid beta Researcher and Organization Principal Investigator AGADJANYAN, MICHAEL G Principal Investigator First Name MICHAEL G Principal Investigator Last Name AGADJANYAN Awardee Organization INSTITUTE FOR MOLECULAR MEDICINE Awardee State California Contact PI Country United States Project Detail Funding Opportunity Announcement PA-13-302: RESEARCH PROJECT GRANT (PARENT R01) FY Overall Cost $615,802 Funding Organization Agency/Funding Organization NINDS Funding Organization Country United States Program Official CORRIVEAU, RODERICK A Related Resources Repository [AlzPED] MultiTEP platform-based DNA epitope vaccine targeting N-terminus of tau induces strong immune responses and reduces tau pathology in THY-Tau22 mice [AlzPED] Comparison of Efficacy of Preventive and Therapeutic Vaccines Targeting the N Terminus of β-Amyloid in an Animal Model of Alzheimer's Disease. [AlzPED] Immunogenicity, efficacy, safety, and mechanism of action of epitope vaccine (Lu AF20513) for Alzheimer's disease: prelude to a clinical trial [AlzPED] Low Concentrations of Anti-Abeta Antibodies Generated in Tg2576 Mice by DNA Epitope Vaccine Fused with 3C3d Molecular Adjuvant Do Not Affect AD Pathology [AlzPED] Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine - a novel immunotherapeutic strategy.
