Project Number 5P01AG020206-10 Agency/Funding Organization NIA Funding Year 2013 View Full Project Details for CELLULAR MECHANISMS OF y-SECRETASE MODULATION AND EFFICACY OF COMBINATION TREATME Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category C. Translational Research and Clinical Interventions 2. Identification and Validation of Novel Targets Researcher and Organization Principal Investigator KOO, EDWARD H. Principal Investigator First Name EDWARD H. Principal Investigator Last Name KOO Awardee Organization UNIVERSITY OF CALIFORNIA SAN DIEGO Awardee State California Contact PI Country United States Project Detail FY Overall Cost $354,127 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official PETANCESKA, SUZANA Related Resources Repository [AlzPED] Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice. [AlzPED] NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ 42 in vivo.