Project Number 2P01AG005119-20A1 Agency/Funding Organization NIA Funding Year 2008 View Full Project Details for BRAIN PROTEIN OXIDATION IN AD; MCI; AND PCAD: ROLES OF AB AND PIN1 Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category A. Molecular Pathogenesis and Physiology of Alzheimer's Disease and Alzheimer's Disease-related Dementias (AD/ADRDs) 8. Cell Death b. Oxidative Stress Researcher and Organization Principal Investigator BUTTERFIELD, D. ALLAN Principal Investigator First Name D. ALLAN Principal Investigator Last Name BUTTERFIELD Awardee Organization UNIVERSITY OF KENTUCKY Awardee State Kentucky Contact PI Country United States Project Detail FY Overall Cost $380,033 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official REFOLO, LORENZO Related Resources Repository [AlzPED] Antisense oligonucleotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer disease. [AlzPED] Early stage drug treatment that normalizes proinflammatory cytokine production attenuates synaptic dysfunction in a mouse model that exhibits age-dependent progression of Alzheimer's disease-related pathology