Project Number 5R01AG018933-09 Agency/Funding Organization NIA Funding Year 2009 View Full Project Details for BETA SECRETASE INHIBITION FOR TREATING ALZHEIMER'S DISEASE Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category C. Translational Research and Clinical Interventions 3. Drug Discovery (small molecules and biologics) a. Amyloid beta Researcher and Organization Principal Investigator TANG, JORDAN J Principal Investigator First Name JORDAN J Principal Investigator Last Name TANG Awardee Organization OKLAHOMA MEDICAL RESEARCH FOUNDATION Awardee State Oklahoma Contact PI Country United States Project Detail FY Overall Cost $479,615 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official BUCKHOLTZ, NEIL Related Resources Repository [AlzPED] Beta-secretase inhibitor GRL-8234 rescues age-related cognitive decline in APP transgenic mice [AlzPED] Amyloid-beta reduction by memapsin 2 (beta-secretase) immunization Patent Compounds for inhibition of memapsin 1 Inhibition of memapsin 1 cleavage in the treatment of diabetes Compounds for treatment of Alzheimer's disease Quinazoline inhibitors of BACE 1 and methods of using
