Project Number 5P01AG010491-14 Agency/Funding Organization NIA Funding Year 2009 View Full Project Details for APOE ISOFORMS AND PROTEIN LEVELS MODULATE A-BETA METABOLISM IN VITRO AND IN VIVO Research Categorization Primary Disease / Condition Alzheimer's Disease CADRO Category A. Molecular Pathogenesis and Physiology of Alzheimer's Disease and Alzheimer's Disease-related Dementias (AD/ADRDs) 4. ApoE and Lipid Neurobiology a. ApoE in Abeta-Mediated AD Pathogenesis Researcher and Organization Principal Investigator MARTINS, RALPH Principal Investigator First Name RALPH Principal Investigator Last Name MARTINS Awardee Organization ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Awardee State New York, N.Y. Contact PI Country United States Project Detail FY Overall Cost $279,282 Funding Organization Agency/Funding Organization NIA Funding Organization Country United States Program Official BUCKHOLTZ, NEIL Related Resources Repository [NIAGADS] Transethnic GWAS Summary Statistics - Jun et al. (2017) [NIAGADS] ADGC Neuropath Summary Stats and Phenotypes- Beecham et al. (2014) [NIAGADS] ADGC Summary Statistics- Naj et al. (2011) [NIAGADS] ADGC African American Summary Statistics- Reitz et al. (2013) [AlzPED] Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model
