Reports, Publications, and Strategic Research Milestones



Recent Journal Publications about CADRO and IADRP


National Alzheimer's Project Act (NAPA) Strategic Plan


AD Research Implementation Milestone Database


Alzheimer's Disease - Research Implementation Area

  • Populations Studies
  • Research on Disease Mechanisms
  • Data Sharing and Reproducibility
  • Translational Infrastructure and Capabilities
  • Drug Development - Existing Targets
  • Drug Development - Novel Targets
  • Drug Repurposing and Combination Therapy Development
  • Non-Pharmacologic Interventions
  • Biomarkers
  • Trial Design
  • Enabling Technologies and Disease Monitoring
  • Recruitment and Citizen Engagement
  • Research on Care and Caregiver Support
  • Public and Private Partnerships
  • Portfolio Analysis Tools and Methods


 Alzheimer's Disease-Related Dementias (ADRD) - Prioritized Research Recommendation Milestones

  • Topic 1: Multiple Etiology Dementias: The Public Health Problem and Improving Recognition across the Spectrum

    • Focus Area 1: Differential Diagnosis
    • Focus Area 2: Epidemiology
  • Topic 2: Health Disparities

    • Focus Area 1: Recruitment
    • Focus Area 2: Advancing Treatment and Prevention Strategies
  • Topic 3: Lewy Body Dementias (LBD): Dementia with Lewy Bodies (DLB) and Parkinson's Disease Dementias (PDD)

    • Focus Area 1: Establish Longitudinal Cohorts with Common Measures, Culminating in Autopsy Studies
    • Focus Area 2: Discover Disease Mechanisms through Brain Mapping and Genetics 
    • Focus Area 3: Develop and Validate Biological and Imaging Biomarkers
    • Focus Area 4: Model Disease Processes to Develop Potential Symptomatic and Disease Modifying Therapies
  • Topic 4: Frontotemporal Dementia (FTD) and Related Tauopathies

    • Focus Area 1: Basic Science - Pathogenesis and Toxicity
    • Focus Area 2: Clinical Science - FTD Clinical Discovery, Tools and Cohorts
  • Topic 5: Vascular Contributions to ADRD: Focus on Small Vessel Disease and AD/Vascular Interactions

    • Focus Area 1: Basic Mechanisms and Experimental Models
    • Focus Area 2: Human-Based Studies